Tamanna (Shilpa Shetty) is a young woman with a rocking career. When she goes for her college reunion, she meets Rohit (Salman Khan). They have a brief affair and Rohit leaves without leaving a contact number. Some time later, when her sister Tanya has an accident, Tamanna offers to donate blood. That’s when Dr. Raisingh (Revathy) tells her that she’s tested positive for HIV. Tamanna’s world goes for a toss when she is not able to contact Rohit and she gets thrown out of her job. She decides to fight the matter in court and hires lawyer Tarun (Abhishek Bachchan) for the same. Will he be able to help Tamanna?